DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans

DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans

Elimination of the proliferating germline extends lifespan in C. elegans. This phenomenon provides a unique platform to understand how complex metazoans retain metabolic homeostasis when challenged with major physiological perturbations. Here, we demonstrate that two conserved transcription regulato...

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Bibliographic Details
Main Authors: Amrit, Francis Raj Gandhi, Steenkiste, Elizabeth Marie, Ratnappan, Ramesh, Chen, Shaw-Wen, McClendon, T. Brooke, Kostka, Dennis, Yanowitz, Judith, Olsen, Carissa Perez, Ghazi, Arjumand
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749232/

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