Background. Hyperlactatemia is a strong predictor of mortality in severe falciparum malaria. Sequestered parasitized erythrocytes and reduced uninfected red blood cell deformability (RCD) compromise microcirculatory flow, leading to anaerobic glycolysis.
Bibliographic Details
| Main Authors: |
Ishioka, Haruhiko,
Ghose, Aniruddha,
Charunwatthana, Prakaykaew,
Maude, Richard,
Plewes, Katherine,
Kingston, Hugh,
Intharabut, Benjamas,
Woodrow, Charlie,
Chotivanich, Kesinee,
Sayeed, Abdullah Abu,
Hasan, Mahtab Uddin,
Day, Nicholas P.,
Faiz, Abul,
White, Nicholas J.,
Hossain, Amir,
Dondorp, Arjen M. |
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| Format: | Online
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| Language: | English |
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| Published: |
Oxford University Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747623/
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