Apigenin blocks IKKα activation and suppresses prostate cancer progression
IKKα has been implicated as a key regulator of oncogenesis and driver of the metastatic process; therefore is regarded as a promising therapeutic target in anticancer drug development. In spite of the progress made in the development of IKK inhibitors, no potent IKKα inhibitor(s) have been identifie...
Main Authors: | Shukla, Sanjeev, Kanwal, Rajnee, Shankar, Eswar, Datt, Manish, Chance, Mark R., Fu, Pingfu, MacLennan, Gregory T., Gupta, Sanjay |
---|---|
Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741599/ |
Similar Items
-
Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice
by: Shukla, Sanjeev, et al.
Published: (2015) -
Plant Flavone Apigenin Binds to Nucleic Acid Bases and Reduces Oxidative DNA Damage in Prostate Epithelial Cells
by: Sharma, Haripaul, et al.
Published: (2014) -
Upregulation of SATB1 Is Associated with Prostate Cancer Aggressiveness and Disease Progression
by: Shukla, Sanjeev, et al.
Published: (2013) -
Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
by: Kanwal, Rajnee, et al.
Published: (2016) -
Correction: Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
by: Kanwal, Rajnee, et al.
Published: (2016)