Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases

Methylation of DNA and histone proteins are mutually involved in the epigenetic regulation of gene expression mediated by DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs). DNMTs methylate cytosine residues within gene promoters, whereas HMTs catalyze the transfer of methyl groups...

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Bibliographic Details
Main Authors: Kanwal, Rajnee, Datt, Manish, Liu, Xiaoqi, Gupta, Sanjay
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033486/