Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
Methylation of DNA and histone proteins are mutually involved in the epigenetic regulation of gene expression mediated by DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs). DNMTs methylate cytosine residues within gene promoters, whereas HMTs catalyze the transfer of methyl groups...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033486/ |