Effects of a novel Nodal-targeting monoclonal antibody in melanoma

Effects of a novel Nodal-targeting monoclonal antibody in melanoma

Nodal is highly expressed in various human malignancies, thus supporting the rationale for exploring Nodal as a therapeutic target. Here, we describe the effects of a novel monoclonal antibody (mAb), 3D1, raised against human Nodal. In vitro treatment of C8161 human melanoma cells with 3D1 mAb shows...

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Bibliographic Details
Main Authors: Strizzi, Luigi, Sandomenico, Annamaria, Margaryan, Naira V., Focà, Annalia, Sanguigno, Luca, Bodenstine, Thomas M., Chandler, Grace S., Reed, David W., Gilgur, Alina, Seftor, Elisabeth A., Seftor, Richard E.B., Khalkhali-Ellis, Zhila, Leonardi, Antonio, Ruvo, Menotti, Hendrix, Mary J.C.
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741437/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741437/

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