Melanocytes Affect Nodal Expression and Signaling in Melanoma Cells: A Lesson from Pediatric Large Congenital Melanocytic Nevi

Expression of Nodal, a Transforming Growth Factor-beta (TGF-β) related growth factor, is associated with aggressive melanoma. Nodal expression in adult dysplastic nevi may predict the development of aggressive melanoma in some patients. A subset of pediatric patients diagnosed with giant or large co...

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Bibliographic Details
Main Authors: Margaryan, Naira V., Gilgur, Alina, Seftor, Elisabeth A., Purnell, Chad, Arva, Nicoleta C., Gosain, Arun K., Hendrix, Mary J. C., Strizzi, Luigi
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813269/