Risperidone-induced weight gain is mediated through shifts in the gut microbiome and suppression of energy expenditure
Risperidone is a second-generation antipsychotic that causes weight gain. We hypothesized that risperidone-induced shifts in the gut microbiome are mechanistically involved in its metabolic consequences. Wild-type female C57BL/6J mice treated with risperidone (80 μg/day) exhibited significant excess...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2015
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740326/ |