The use of the NIS reporter gene for optimizing oncolytic virotherapy
Introduction: Oncolytic viruses are experimental cancer therapies being translated to the clinic. They are unique in their ability to amplify within the body, therefore requiring careful monitoring of viral replication and biodistribution. Traditional monitoring strategies fail to recapitulate the...
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Taylor & Francis
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732458/ |
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pubmed-47324582016-02-16 The use of the NIS reporter gene for optimizing oncolytic virotherapy Miller, Amber Russell, Stephen J Reviews Introduction: Oncolytic viruses are experimental cancer therapies being translated to the clinic. They are unique in their ability to amplify within the body, therefore requiring careful monitoring of viral replication and biodistribution. Traditional monitoring strategies fail to recapitulate the dynamic nature of oncolytic virotherapy. Consequently, clinically relevant, noninvasive, high resolution strategies are needed to effectively track virotherapy in real time. Taylor & Francis 2016-01-02 2015-10-12 /pmc/articles/PMC4732458/ /pubmed/26457362 http://dx.doi.org/10.1517/14712598.2016.1100162 Text en © 2015 The Author(s). Published by Taylor & Francis. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Miller, Amber Russell, Stephen J |
| spellingShingle |
Miller, Amber Russell, Stephen J The use of the NIS reporter gene for optimizing oncolytic virotherapy |
| author_facet |
Miller, Amber Russell, Stephen J |
| author_sort |
Miller, Amber |
| title |
The use of the NIS reporter gene for optimizing oncolytic virotherapy |
| title_short |
The use of the NIS reporter gene for optimizing oncolytic virotherapy |
| title_full |
The use of the NIS reporter gene for optimizing oncolytic virotherapy |
| title_fullStr |
The use of the NIS reporter gene for optimizing oncolytic virotherapy |
| title_full_unstemmed |
The use of the NIS reporter gene for optimizing oncolytic virotherapy |
| title_sort |
use of the nis reporter gene for optimizing oncolytic virotherapy |
| description |
Introduction: Oncolytic viruses are experimental cancer therapies being translated to the clinic. They are unique in their ability to amplify within the body, therefore requiring careful monitoring of viral replication and biodistribution. Traditional monitoring strategies fail to recapitulate the dynamic nature of oncolytic virotherapy. Consequently, clinically relevant, noninvasive, high resolution strategies are needed to effectively track virotherapy in real time. |
| publisher |
Taylor & Francis |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732458/ |
| _version_ |
1613530490478788608 |