CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells
PHD1 (also known as EGLN2) belongs to a family of prolyl hydroxylases (PHDs) that are involved in the control of the cellular response to hypoxia. PHD1 is also able to regulate mitotic progression through the regulation of the crucial centrosomal protein Cep192, establishing a link between the oxyge...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists Ltd
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732302/ |