Characterization of the Oxidative Degradation Product of Darunavir by LC-MS/MS

Characterization of the Oxidative Degradation Product of Darunavir by LC-MS/MS

A rapid, selective, and reliable LC-MSn method has been developed and validated for the isolation and structural characterization of the degradation product of darunavir (DRV). DRV, an HIV-1 protease inhibitor, was subjected to intrinsic oxidative stress conditions using 30% hydrogen peroxide and th...

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Bibliographic Details
Main Authors: Yamjala, Karthik, Atukuri, Jeevitha, Nagappan, Krishnaveni, Halekote Shivaraju, Nivedeetha, Subramania Nainar, Meyyanathan
Format: Online
Language:English
Published: The Austrian Journal of Pharmaceutical Sciences 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727738/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727738/

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