Crystal structure and SUMO binding of Slx1-Slx4 complex

The SLX1-SLX4 complex is a structure-specific endonuclease that cleaves branched DNA structures and plays significant roles in DNA recombination and repair in eukaryotic cells. The heterodimeric interaction between SLX1 and SLX4 is essential for the endonuclease activity of SLX1. Here, we present th...

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Bibliographic Details
Main Authors: Lian, Fu-Ming, Xie, Si, Qian, Chengmin
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726241/