Overexpression of Heme Oxygenase-1 Prevents Renal Interstitial Inflammation and Fibrosis Induced by Unilateral Ureter Obstruction

Renal fibrosis plays an important role in the onset and progression of chronic kidney diseases. Many studies have demonstrated that heme oxygenase-1 (HO-1) is involved in diverse biological processes as a cytoprotective molecule, including anti-inflammatory, anti-oxidant, anti-apoptotic, antiprolife...

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Main Authors: Chen, Xiao, Wei, Shi-Yao, Li, Jian-Si, Zhang, Qing-Fang, Wang, Yu-Xiao, Zhao, Shi-Lei, Yu, Jing, Wang, Chang, Qin, Ying, Wei, Qiu-Ju, Lv, Gui-Xiang, Li, Bing
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713170/