Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Serial femtosecond crystallography (SFX) using X-ray free-electron lasers has produced high-resolution, room temperature, time-resolved protein structures. We report preliminary SFX of Sindbis virus, an enveloped icosahedral RNA virus with ∼700 Å diameter. Microcrystals delivered in viscous agarose...

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Bibliographic Details
Main Authors: Lawrence, Robert M., Conrad, Chelsie E., Zatsepin, Nadia A., Grant, Thomas D., Liu, Haiguang, James, Daniel, Nelson, Garrett, Subramanian, Ganesh, Aquila, Andrew, Hunter, Mark S., Liang, Mengning, Boutet, Sébastien, Coe, Jesse, Spence, John C. H., Weierstall, Uwe, Liu, Wei, Fromme, Petra, Cherezov, Vadim, Hogue, Brenda G.
Format: Online
Language:English
Published: American Crystallographic Association 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711640/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711640/

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