Killer Artificial Antigen Presenting Cells (KaAPC) for Efficient In Vitro Depletion of Human Antigen-specific T Cells

Current treatment of T cell mediated autoimmune diseases relies mostly on strategies of global immunosuppression, which, in the long term, is accompanied by adverse side effects such as a reduced ability to control infections or malignancies. Therefore, new approaches need to be developed that targe...

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Bibliographic Details
Main Authors: Schütz, Christian, Fleck, Martin, Schneck, Jonathan P., Oelke, Mathias
Format: Online
Language:English
Published: MyJove Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710085/