Artificial Antigen Presenting Cell (aAPC) Mediated Activation and Expansion of Natural Killer T Cells

Natural killer T (NKT) cells are a unique subset of T cells that display markers characteristic of both natural killer (NK) cells and T cells1. Unlike classical T cells, NKT cells recognize lipid antigen in the context of CD1 molecules2. NKT cells express an invariant TCRα chain rearrangement: Vα14J...

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Bibliographic Details
Main Authors: East, James E., Sun, Wenji, Webb, Tonya J.
Format: Online
Language:English
Published: MyJove Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577866/