The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering
Cohesin tethers together regions of DNA, thereby mediating higher order chromatin organization that is critical for sister chromatid cohesion, DNA repair and transcriptional regulation. Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPase comprised of Smc1 and Smc3 ATPase active sites....
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709263/ |