Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development
Regulatory elements are more evolutionarily conserved and provide a larger mutational target than coding regions of the human genome, suggesting that mutations in non-coding regions contribute significantly to development and disease. Using a computational approach to predict gene regulatory enhance...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Springer Berlin Heidelberg
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701781/ |