The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKL

The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKL

Tumor cell metastasis is a complex process that has been mechanistically linked to the epithelial-mesenchymal transition (EMT). The double-negative feedback loop between the microRNA-200 family and the Zeb1 transcriptional repressor is a master EMT regulator, but there is incomplete understanding of...

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Bibliographic Details
Main Authors: Ungewiss, Christin, Rizvi, Zain H., Roybal, Jonathon D., Peng, David H., Gold, Kathryn A., Shin, Dong-Hoon, Creighton, Chad J., Gibbons, Don L.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700473/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700473/

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