CRKL oncogene is downregulated by p53 through miR-200s

Tumor suppressive miRNAs that target oncogenes are frequently downregulated in cancers, and this downregulation leads to oncogene pathway activation. Thus, tumor suppressive miRNAs and their target oncogenes have been proposed as useful targets in cancer treatment. miR-200 family downregulation has...

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Bibliographic Details
Main Authors: Tamura, Miyuki, Sasaki, Yasushi, Kobashi, Kenta, Takeda, Kousuke, Nakagaki, Takafumi, Idogawa, Masashi, Tokino, Takashi
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556393/