Modified mRNA as an alternative to plasmid DNA (pDNA) for transcript replacement and vaccination therapy
Introduction: Current gene therapy involves replacement of defective gene by delivery of healthy genetic material to precede normal function. Virus-mediated gene delivery is the most successful and efficient method for gene therapy, but it has been challenged due to serious safety concerns. Convers...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Informa Healthcare
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696419/ |