Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity

Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity

IRE1α is an endoplasmic reticulum (ER)-resident transmembrane signaling protein and a cellular stress sensor. The protein harbors a cytosolic dual kinase/endoribonuclease activity required for adaptive responses to micro-environmental changes. In an orthotopic xenograft model of human glioma, invali...

Full description

Bibliographic Details
Main Authors: Jabouille, Arnaud, Delugin, Maylis, Pineau, Raphaël, Dubrac, Alexandre, Soulet, Fabienne, Lhomond, Stéphanie, Pallares-Lupon, Nestor, Prats, Hervé, Bikfalvi, Andreas, Chevet, Eric, Touriol, Christian, Moenner, Michel
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694804/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694804/

Similar Items