Cerebrospinal Fluid Culture Positivity and Clinical Outcomes After Amphotericin-Based Induction Therapy for Cryptococcal Meningitis

Background. Amphotericin-based combination antifungal therapy reduces mortality from human immunodeficiency virus (HIV)-associated cryptococcal meningitis. However, 40%–50% of individuals have positive cerebrospinal fluid (CSF) fungal cultures at completion of 2 weeks of amphotericin induction thera...

Full description

Bibliographic Details
Main Authors: Rolfes, Melissa A., Rhein, Joshua, Schutz, Charlotte, Taseera, Kabanda, Nabeta, Henry W., Huppler Hullsiek, Kathy, Akampuira, Andrew, Rajasingham, Radha, Musubire, Abdu, Williams, Darlisha A., Thienemann, Friedrich, Bohjanen, Paul R., Muzoora, Conrad, Meintjes, Graeme, Meya, David B., Boulware, David R.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692307/