Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer

A gene drug delivery system for glioma therapy based on transferrin (Tf)-modified polyamidoamine dendrimer (PAMAM) was prepared. Gene drug, tumor necrosis factor-related apoptosis-inducing ligand (hTRAIL)-encoding plasmid open reading frame (pORF-hTRAIL, Trail), was condensed by Tf-modified PAMAM to...

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Bibliographic Details
Main Authors: Gao, Song, Li, Jianfeng, Jiang, Chen, Hong, Bo, Hao, Bing
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690643/