Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer
A gene drug delivery system for glioma therapy based on transferrin (Tf)-modified polyamidoamine dendrimer (PAMAM) was prepared. Gene drug, tumor necrosis factor-related apoptosis-inducing ligand (hTRAIL)-encoding plasmid open reading frame (pORF-hTRAIL, Trail), was condensed by Tf-modified PAMAM to...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690643/ |