A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes

Current first-line treatments for uncomplicated falciparum malaria rapidly clear the asexual stages of the parasite, but do not fully prevent parasite transmission by mosquitoes. The standard membrane feeding assay (SMFA) is the biological gold standard assessment of transmission reducing activity (...

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Bibliographic Details
Main Authors: Vos, Martijn W., Stone, Will J. R., Koolen, Karin M., van Gemert, Geert-Jan, van Schaijk, Ben, Leroy, Didier, Sauerwein, Robert W., Bousema, Teun, Dechering, Koen J.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685452/