Turnover of Focal Adhesions and Cancer Cell Migration

Cells are usually surrounded by the extracellular matrix (ECM), and adhesion of the cells to the ECM is a key step in their migration through tissues. Integrins are important receptors for the ECM and form structures called focal adhesions (FAs). Formation and disassembly of FAs are regulated dynami...

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Bibliographic Details
Main Authors: Nagano, Makoto, Hoshino, Daisuke, Koshikawa, Naohiko, Akizawa, Toshifumi, Seiki, Motoharu
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272802/