Mutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism Etiology

Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder with a strong but complex genetic component. Recent family based exome-sequencing strategies have identified recurrent de novo mutations at specific genes, providing strong evidence for ASD risk, but also highlighting the extreme...

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Bibliographic Details
Main Authors: Barnard, Rebecca A., Pomaville, Matthew B., O'Roak, Brian J.
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681771/