RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes

Fluctuations in mRNA levels only partially contribute to determine variations in mRNA availability for translation, producing the well-known poor correlation between transcriptome and proteome data. Recent advances in microscopy now enable researchers to obtain high resolution images of ribosomes on...

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Bibliographic Details
Main Authors: Lauria, Fabio, Tebaldi, Toma, Lunelli, Lorenzo, Struffi, Paolo, Gatto, Pamela, Pugliese, Andrea, Brigotti, Maurizio, Montanaro, Lorenzo, Ciribilli, Yari, Inga, Alberto, Quattrone, Alessandro, Sanguinetti, Guido, Viero, Gabriella
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678843/