RNAi revised - target mRNA-dependent enhancement of gene silencing

The discovery of RNA interference (RNAi) gave rise to the development of new nucleic acid-based technologies as powerful investigational tools and potential therapeutics. Mechanistic key details of RNAi in humans need to be deciphered yet, before such approaches take root in biomedicine and molecula...

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Bibliographic Details
Main Authors: Dornseifer, Simon, Willkomm, Sarah, Far, Rosel Kretschmer-Kazemi, Liebschwager, Janine, Beltsiou, Foteini, Frank, Kirsten, Laufer, Sandra D., Martinetz, Thomas, Sczakiel, Georg, Claussen, Jens Christian, Restle, Tobias
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678823/