Specific binding of a hexanucleotide to HIV-1 reverse transcriptase: a novel class of bioactive molecules

Short oligonucleotides below 8–10 nt in length adopt relatively simple structures. Accordingly, they represent interesting and so far unexplored lead compounds as molecular tools and, potentially, for drug development as a rational improvement of efficacy seem to be less complex than for other class...

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Bibliographic Details
Main Authors: Mescalchin, Alessandra, Wünsche, Winfried, Laufer, Sandra D., Grohmann, Dina, Restle, Tobias, Sczakiel, Georg
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635251/