CARTS biogenesis requires VAP–lipid transfer protein complexes functioning at the endoplasmic reticulum–Golgi interface

Biogenesis of the TGN-derived transport carriers CARTS requires the ER protein VAP and Golgi lipid transfer proteins, ceramide transfer protein and OSBP. Sac1 lipid phosphatase is recruited to a VAP–OSBP complex formed at an ER subdomain closely apposed to the trans-Golgi/TGN. Association–dissociati...

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Bibliographic Details
Main Authors: Wakana, Yuichi, Kotake, Richika, Oyama, Nanako, Murate, Motohide, Kobayashi, Toshihide, Arasaki, Kohei, Inoue, Hiroki, Tagaya, Mitsuo
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678024/