CARTS biogenesis requires VAP–lipid transfer protein complexes functioning at the endoplasmic reticulum–Golgi interface
Biogenesis of the TGN-derived transport carriers CARTS requires the ER protein VAP and Golgi lipid transfer proteins, ceramide transfer protein and OSBP. Sac1 lipid phosphatase is recruited to a VAP–OSBP complex formed at an ER subdomain closely apposed to the trans-Golgi/TGN. Association–dissociati...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678024/ |