dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest

Nutrient availability has profound influence on development. In the nematode C. elegans, nutrient availability governs post-embryonic development. L1-stage larvae remain in a state of developmental arrest after hatching until they feed. This “L1 arrest” (or "L1 diapause") is associated wit...

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Bibliographic Details
Main Authors: Kaplan, Rebecca E. W., Chen, Yutao, Moore, Brad T., Jordan, James M., Maxwell, Colin S., Schindler, Adam J., Baugh, L. Ryan
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676721/