Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia

Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia

Minimal Residual Disease (MRD) detection can be used for early intervention in relapse, risk stratification, and treatment guidance. FLT3 ITD is the most common mutation found in AML patients with normal karyotype. We evaluated the feasibility of NGS with high coverage (up to 2.4.106 PE fragments) f...

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Bibliographic Details
Main Authors: Bibault, Jean-Emmanuel, Figeac, Martin, Hélevaut, Nathalie, Rodriguez, Céline, Quief, Sabine, Sebda, Shéhérazade, Renneville, Aline, Nibourel, Olivier, Rousselot, Philippe, Gruson, Bérengère, Dombret, Hervé, Castaigne, Sylvie, Preudhomme, Claude
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673201/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673201/

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