Akt phosphorylates Prohibitin 1 to mediate its mitochondrial localization and promote proliferation of bladder cancer cells

Bladder cancer (BC) is very common and associated with significant morbidity and mortality, though the molecular underpinnings of its origination and progression remain poorly understood. In this study, we demonstrate that Prohibitin 1 (PHB) was overexpressed in human BC tissues and that PHB upregul...

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Bibliographic Details
Main Authors: Jiang, L, Dong, P, Zhang, Z, Li, C, Li, Y, Liao, Y, Li, X, Wu, Z, Guo, S, Mai, S, Xie, D, Liu, Z, Zhou, F
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669803/