Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives
Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for pancreatic beta-cell toxicity, leading to a transition from a state of insulin resistance to type II diabetes through the loss of insulin producing...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662995/ |