Lewis acid-promoted hydrofluorination of alkynyl sulfides to generate α-fluorovinyl thioethers
A new method for the preparation of α-fluorovinyl thioethers is reported which involves the hydrofluorination of alkynyl sulfides with 3HF·Et3N, a process that requires Lewis acid activation using BF3·Et2O and TiF4. The method gives access to a range of α-fluorovinyl thioethers, some in high stereos...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Beilstein-Institut
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661019/ |