Synthesis of uniform cyclodextrin thioethers to transport hydrophobic drugs

Methyl and ethyl thioether groups were introduced at all primary positions of α-, β-, and γ-cyclodextrin by nucleophilic displacement reactions starting from the corresponding per-(6-deoxy-6-bromo)cyclodextrins. Further modification of all 2-OH positions by etherification with iodo terminated trieth...

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Bibliographic Details
Main Authors: Becker, Lisa F, Schwarz, Dennis H, Wenz, Gerhard
Format: Online
Language:English
Published: Beilstein-Institut 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273231/