LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer

LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer

lncRNAs play important roles in the epigenetic regulation of carcinogenesis and progression. Previous studies suggest that HOTAIR contributes to gastric cancer (GC) development, and the overexpression of HOTAIR predicts a poor prognosis. In this study, we found that HOTAIR was more highly expressed...

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Bibliographic Details
Main Authors: Liu, Y-w, Sun, M, Xia, R, Zhang, E-b, Liu, X-h, Zhang, Z-h, Xu, T-p, De, W, Liu, B-r, Wang, Z-x
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650715/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650715/

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