A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers
Immortality is an essential characteristic of human carcinoma cells. We recently developed an efficient, reproducible method that immortalizes human mammary epithelial cells (HMEC) in the absence of gross genomic changes by targeting 2 critical senescence barriers. Consistent transcriptomic changes...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Taylor & Francis
2015
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844203/ |