ER stress induces NLRP3 inflammasome activation and hepatocyte death

ER stress induces NLRP3 inflammasome activation and hepatocyte death

The incidence of chronic liver disease is constantly increasing, owing to the obesity epidemic. However, the causes and mechanisms of inflammation-mediated liver damage remain poorly understood. Endoplasmic reticulum (ER) stress is an initiator of cell death and inflammatory mechanisms. Although obe...

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Bibliographic Details
Main Authors: Lebeaupin, C, Proics, E, de Bieville, C H D, Rousseau, D, Bonnafous, S, Patouraux, S, Adam, G, Lavallard, V J, Rovere, C, Le Thuc, O, Saint-Paul, M C, Anty, R, Schneck, A S, Iannelli, A, Gugenheim, J, Tran, A, Gual, P, Bailly-Maitre, B
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650444/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650444/

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