Toxicity of Amphotericin B Deoxycholate-Based Induction Therapy in Patients with HIV-Associated Cryptococcal Meningitis

Amphotericin B deoxycholate (AmBd) is the recommended induction treatment for HIV-associated cryptococcal meningitis (CM). Its use is hampered by toxicities that include electrolyte abnormalities, nephrotoxicity, and anemia. Protocols to minimize toxicity are applied inconsistently. In a clinical tr...

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Bibliographic Details
Main Authors: Bicanic, Tihana, Bottomley, Christian, Loyse, Angela, Brouwer, Annemarie E., Muzoora, Conrad, Taseera, Kabanda, Jackson, Arthur, Phulusa, Jacob, Hosseinipour, Mina C., van der Horst, Charles, Limmathurotsakul, Direk, White, Nicholas J., Wilson, Douglas, Wood, Robin, Meintjes, Graeme, Harrison, Thomas S., Jarvis, Joseph N.
Format: Online
Language:English
Published: American Society for Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649151/