Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage*
Background: IL-1β is an inflammatory cytokine that is activated by cleavage of an inactive precursor. Multiple proteases can cleave IL-1β, but their contribution under disease conditions is unknown.
Main Authors: | Edye, Michelle E., Brough, David, Allan, Stuart M. |
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Format: | Online |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646186/ |
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