Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage*
Background: IL-1β is an inflammatory cytokine that is activated by cleavage of an inactive precursor. Multiple proteases can cleave IL-1β, but their contribution under disease conditions is unknown.
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
American Society for Biochemistry and Molecular Biology
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646186/ |