Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation

Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation

Vascular calcification, a pathologic response to defective calcium and phosphate homeostasis, is strongly associated with cardiovascular mortality and morbidity. In this study, we have observed that pyruvate dehydrogenase kinase 4 (PDK4) is upregulated and pyruvate dehydrogenase complex phosphorylat...

Full description

Bibliographic Details
Main Authors: Lee, Sun Joo, Jeong, Ji Yun, Oh, Chang Joo, Park, Sungmi, Kim, Joon-Young, Kim, Han-Jong, Doo Kim, Nam, Choi, Young-Keun, Do, Ji-Yeon, Go, Younghoon, Ha, Chae-Myung, Choi, Je-Yong, Huh, Seung, Ho Jeoung, Nam, Lee, Ki-Up, Choi, Hueng-Sik, Wang, Yu, Park, Keun-Gyu, Harris, Robert A., Lee, In-Kyu
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642318/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642318/

Similar Items