Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers
Impaired glucose homeostasis is one of the risk factors for causing metabolic diseases including obesity, type 2 diabetes, and cancers. In glucose metabolism, pyruvate dehydrogenase complex (PDC) mediates a major regulatory step, an irreversible reaction of oxidative decarboxylation of pyruvate to a...
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| Format: | Online |
| Language: | English |
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Korean Diabetes Association
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483603/ |