Acquisition of cancer stem cell-like properties in non-small cell lung cancer with acquired resistance to afatinib

Acquisition of cancer stem cell-like properties in non-small cell lung cancer with acquired resistance to afatinib

Afatinib is an irreversible epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) that is known to be effective against the EGFR T790M variant, which accounts for half of the mechanisms of acquired resistance to reversible EGFR-TKIs. However, acquired resistance to afatinib was als...

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Bibliographic Details
Main Authors: Hashida, Shinsuke, Yamamoto, Hiromasa, Shien, Kazuhiko, Miyoshi, Yuichiro, Ohtsuka, Tomoaki, Suzawa, Ken, Watanabe, Mototsugu, Maki, Yuho, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Miyoshi, Shinichiro, Toyooka, Shinichi
Format: Online
Language:English
Published: John Wiley & Sons, Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638008/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638008/

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