Structural basis for phosphatidylinositol-phosphate biosynthesis
Phosphatidylinositol is critical for intracellular signalling and anchoring of carbohydrates and proteins to outer cellular membranes. The defining step in phosphatidylinositol biosynthesis is catalysed by CDP-alcohol phosphotransferases, transmembrane enzymes that use CDP-diacylglycerol as donor su...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634129/ |