Structural basis for catalysis in a CDP-alcohol phosphotransferase

Structural basis for catalysis in a CDP-alcohol phosphotransferase

The CDP-alcohol phosphotransferase (CDP-AP) family of integral membrane enzymes catalyzes the transfer of a substituted phosphate group from a CDP-linked donor to an alcohol-acceptor. This is an essential reaction for phospholipid biosynthesis across all kingdoms of life, and it is catalyzed solely...

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Bibliographic Details
Main Authors: Sciara, Giuliano, Clarke, Oliver B., Tomasek, David, Kloss, Brian, Tabuso, Shantelle, Byfield, Rushelle, Cohn, Raphael, Banerjee, Surajit, Rajashankar, Kanagalaghatta R., Slavkovic, Vesna, Graziano, Joseph H., Shapiro, Lawrence, Mancia, Filippo
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098843/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098843/

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