S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide

S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide

•Hydrogen peroxide is both a toxin and an endogenous signaling molecule.•The use of hydrogen peroxide mouthwash causes ROS mediated damage in cheek cells.•S-glutathionylated proteins are biomarkers for this damage.•S-glutathionylated proteins may be of future value as pharmacodynamic markers....

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Main Authors: Grek, Christina L., Reyes, Leticia, Townsend, Danyelle M., Tew, Kenneth D.
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633976/
id pubmed-4633976
recordtype oai_dc
spelling pubmed-46339762015-12-15 S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide Grek, Christina L. Reyes, Leticia Townsend, Danyelle M. Tew, Kenneth D. Regular Article •Hydrogen peroxide is both a toxin and an endogenous signaling molecule.•The use of hydrogen peroxide mouthwash causes ROS mediated damage in cheek cells.•S-glutathionylated proteins are biomarkers for this damage.•S-glutathionylated proteins may be of future value as pharmacodynamic markers. Elsevier 2014-09-03 /pmc/articles/PMC4633976/ /pubmed/26673080 http://dx.doi.org/10.1016/j.bbacli.2014.08.003 Text en © 2014 Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Grek, Christina L.
Reyes, Leticia
Townsend, Danyelle M.
Tew, Kenneth D.
spellingShingle Grek, Christina L.
Reyes, Leticia
Townsend, Danyelle M.
Tew, Kenneth D.
S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide
author_facet Grek, Christina L.
Reyes, Leticia
Townsend, Danyelle M.
Tew, Kenneth D.
author_sort Grek, Christina L.
title S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide
title_short S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide
title_full S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide
title_fullStr S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide
title_full_unstemmed S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide
title_sort s-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide
description •Hydrogen peroxide is both a toxin and an endogenous signaling molecule.•The use of hydrogen peroxide mouthwash causes ROS mediated damage in cheek cells.•S-glutathionylated proteins are biomarkers for this damage.•S-glutathionylated proteins may be of future value as pharmacodynamic markers.
publisher Elsevier
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633976/
_version_ 1613497736532852736

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