UXT, a novel MDMX-binding protein, promotes glycolysis by mitigating p53-mediated restriction of NF-κB activity
The importance of stress-induced p53 activation has been extensively investigated and well established. How the basal activity of p53 prevents carcinogenesis, however, remains incompletely understood. We report the identification of a novel p53 inhibitor, UXT, which binds to MDMX and suppresses the...
Main Authors: | Qi, Min, Ganapathy, Suthakar, Zeng, Weiqi, Zhang, Jianglin, Little, John B., Yuan, Zhi-Min |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627330/ |
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