Low-dose Arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation

Low-dose Arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation

Most chemotherapeutical drugs kill cancer cells chiefly by inducing DNA damage, which unfortunately also causes undesirable injuries to normal tissues, mainly due to p53 activation. We report a novel strategy of normal tissue-protection that involves p53/NF-κB coordinated metabolic regulation. Pretr...

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Bibliographic Details
Main Authors: Ganapathy, Suthakar, Xiao, Shaowen, Seo, Seog-Jin, Lall, Rajuli, Yang, Mei, Xu, Teng, Su, Hang, Shadfan, Miriam, Ha, Chul S., Yuan, Zhi-Min
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467814/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467814/

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